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首页 >  资讯  >  行业资讯  >  国自然科学基金委:通报这10项科研不端案件处理决定

国自然科学基金委:通报这10项科研不端案件处理决定

2022-05-13 17:21:18  来源: 分析测试百科网

  国家自然科学基金委员会坚决贯彻落实中共中央办公厅、国务院办公厅《关于进一步加强科研诚信建设的若干意见》《关于进一步弘扬科学家精神加强作风和学风建设的意见》精神,为净化学术生态,保障高水平科技自立自强,持续深入开展科研诚信建设,对涉及国家自然科学基金的科研不端行为进行严肃查处。国家自然科学基金委员会监督委员会对受理的科研诚信案件开展调查核实、综合研判,依照《国家自然科学基金条例》《国家自然科学基金委员会监督委员会对科学基金资助工作中不端行为的处理办法(试行)》《国家自然科学基金项目科研不端行为调查处理办法》等法规制度提出处理建议。国家自然科学基金委员会2022年度第2次委务会议经审议,决定对相关涉事主体进行处理。现将其中给予通报批评的10份处理决定(网络发布版)予以公布。

关于对吴冬梅、郑元林、陆军等发表的论文存在图片或数据造假、编造研究过程和未经同意使用他人署名以及项目结题报告中存在虚假信息等问题的处理决定

国科金监处〔2022〕1号

  国家自然科学基金委员会监督委员会对江苏师范大学吴冬梅、郑元林、陆军等多篇论文涉嫌学术不端开展了调查,涉事论文如下:

  论文1:“Lu, Hong-Jie#; Yan, Jing#; Jin, Pei-Ying#; Zheng, Gui-Hong; Qin, Su-Ming; Wu, Dong-Mei*; Lu, Jun*; Zheng, Yuan-Lin*. MicroRNA-152 inhibits tumor cell growth while inducing apoptosis via the transcriptional repression of cathepsin L in gastrointestinal stromal tumor. Cancer Biomarkers, 2018, 21(3):711-722.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文2:“Dong-Mei Wu, Xin Wen, Xin-Rui Han, Shan Wang, Yong-Jian Wang, Min Shen, Shao-Hua Fan, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Jun Lu*, Yuan-Lin Zheng*, Gui-Quan Chen*. Reduced LINC00540 Expression Inhibits Human Hepatocellular Carcinoma Progression and Metastasis via the NKD2-Dependent Wnt/β-Catenin Pathway. SSRN Electronic Journal, 2019.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文3:“Xin Wen#, Jing Yan#, Xin-Rui Han#, Gui-Hong Zheng, Ran Tang, Li-Fang Liu, Dong-Mei Wu, Jun Lu*, Yuan-Lin Zheng*. PTEN gene silencing contributes to airway remodeling and induces airway smooth muscle cell proliferation in mice with allergic asthma. Journal of Thoracic Disease,2018, 10(1):202-211.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文4:“Zi-Feng Zhang#, Yong-Jian Wang#, Shao-Hua Fan, Shi-Xin Du, Xue-Dong Li, Dong-Mei Wu*, Jun Lu* and Yuan-Lin Zheng*. MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9.Oncotarget, 2017, 8(60):101345-101361.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文5:“Yong-Jian Wang#, Zi-Feng Zhang#, Shao-Hua Fan, Juan Zhuang, Qun Shan, Xin-Rui Han, Xin Wen, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Bin Qiao, Qian Tao, Dong-Mei Wu*, Jun Lu* and Yuan-Lin Zheng*. MicroRNA-433 inhibits oral squamous cell carcinoma cells by targeting FAK. Oncotarget, 2017, 8(59):100227-100241.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文6:“Xin-Rui Han#, Xin Wen#, Yong-Jian Wang#, Shan Wang, Min Shen, Zi-Feng Zhang, Shao-Hua Fan, Qun Shan, Liang Wang, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*and Yuan-Lin Zheng*. Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia. Molecular Medicine, 2018, 24:18.”(标注基金号81271225、81171012、30950031、81571055、81400902、81570531、81672731)

  论文7:“Hong-Jie Lu#, Jing Yan#, Pei-Ying Jin#, Gui-Hong Zheng#, Hai-Lin Zhang#, Ming Bai#, Dong-Mei Wu*, Jun Lu*, and Yuan-Lin Zheng*. Mechanism of MicroRNA-708 Targeting BAMBI in Cell Proliferation, Migration, and Apoptosis in Mice With Melanoma via the Wnt and TGF-β Signaling Pathways. Technology in Cancer Research & Treatment, 2018, 17:1-15.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文8:“Dong-Mei Wu#, Shan Wang#, Xin Wen, Xin-Rui Han, Yong-Jian Wang, Min Shen, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Jun Lu*, Yuan-Lin Zheng*. Inhibition of microRNA-200a Upregulates the Expression of Striatal Dopamine Receptor D2 to Repress Apoptosis of Striatum via the cAMP/PKA Signaling Pathway in Rats with Parkinson’s Disease. Cellular Physiology and Biochemistry, 2018, 51:1600-1615.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文9:“Dong-Mei Wu#, Xin-Rui Han#, Xin Wen#, Shan Wang, Yong-Jian Wang, Min Shen, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Jun Lu*, Yuan-Lin Zheng*. Long Non-Coding RNA LINC01260 Inhibits the Proliferation, Migration and Invasion of Spinal Cord Glioma Cells by Targeting CARD11 Via the NF-κB Signaling Pathway. Cellular Physiology and Biochemistry, 2018, 48:1563-1578.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文10:“Dong-Mei Wu#, Xin-Rui Han#, Xin Wen#, Shan Wang, Shao-Hua Fan, Juan Zhuang, Yong-Jian Wang, Zi-Feng Zhang, Meng-Qiu Li, Bin Hu, Qun Shan, Chun-Hui Sun, Jun Lu*, Yuan-Lin Zheng*. Salidroside Protection Against Oxidative Stress Injury Through the Wnt/β-Catenin Signaling Pathway in Rats with Parkinson’s Disease. Cellular Physiology and Biochemistry, 2018, 46:1793-1806.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文11:“Dong-Mei Wu#, Xin Wen#, Xin-Rui Han#, Shan Wang, Yong-Jian Wang, Min Shen,Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Jun Lu*, and Yuan-Lin Zheng*. Micro-RNA-143 inhibits proliferation and promotes apoptosis of thymocytes by targeting CXCL13 in a myasthenia gravis mouse model. AJP Cell Physiology, 2019, 316:C70-C80.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文12:“Dong-Mei Wu#, Shan Wang#, Xin Wen, Xin-Rui Han, Yong-Jian Wang, Shao-Hua Fan, Zi-Feng Zhang, Qun Shan, Jun Lu*, and Yuan-Lin Zheng*. MircoRNA-1275 promotes proliferation, invasion and migration of glioma cells via SERPINE1. Journal of Cellular and Molecular Medicine, 2018, 22:4963-4974.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文13:“Xin-Rui Han#, Xin Wen#, Yong-Jian Wang#, Shan Wang, Min Shen, Zi-Feng Zhang, Shao-Hua Fan, Qun Shan, Liang Wang, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. MicroRNA-140-5p elevates cerebral protection of dexmedetomidine against hypoxic-ischaemic brain damage via the Wnt/β-cateninsignalling pathway. Journal of Cellular and Molecular Medicine, 2018, 22:3167-3182.”(标注基金号81271225、81171012、30950031、81571055、81400902、81570531、81672731)

  论文14:“Dong-Mei Wu#, Yong-Jian Wang#, Xin-Rui Han, Xin Wen, Lei Li, Lan Xu, Jun Lu*, Yuan-Lin Zheng*. Tanshinone IIA prevents left ventricular remodelling via the TLR4/MyD88/NF-κBsignalling pathway in rats with myocardial infarction. Journal of Cellular and Molecular Medicine, 2018, 22:3058-3072.”(标注基金号81271225、81171012、30950031、81571055、81400902、81570531、81672731)

  论文15:“Dong-Mei Wu#, Shan Wang#, Min Shen#, Yong-Jian Wang, Bo Zhang, Zi-Qi Wu, Jun Lu*, Yuan-Lin Zheng*. S100A9 gene silencing inhibits the release of pro-inflammatory cytokines by blocking the IL-17 signalling pathway in mice with acute pancreatitis. Journal of Cellular and Molecular Medicine, 2018, 22:2378-2389.”(标注基金号81271225、81171012、30950031、81571055、81400902、81570531、81672731)

  论文16:“Shan Wang#, Xin Wen#, Xin-Rui Han, Yong-Jian Wang,Min Shen, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan,Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Repression of microRNA-382 inhibits glomerular mesangial cell proliferation and extracellular matrix accumulation via FoxO1 in mice with diabetic nephropathy. Cell Proliferation, 2018, e12462.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文17:“Yao Tang#, Qi-Hang Cai#, Yong-Jian Wang, Shao-Hua Fan, Zi-Feng Zhang, Meng-Qi Xiao, Jin-Yu Zhu, Dong-Mei Wu*, Jun Lu* and Yuan-Lin Zheng*. Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD. Bioscience Report, 2017, 37(6).”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文18:“Xin Wen#, Xin-Rui Han#, Shao-Hua Fan, Zi-Feng Zhang, Lu Chen, Gao Yi, Dong-Mei Wu*, Jun Lu* and Yuan-Lin Zheng*. Down-regulation of XIAP enhances the radiosensitivity of esophageal cancer cells in vivo and in vitro. Bioscience Report, 2017, 37(5).”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文19:“Hong-Jie Lu#, Pei-Ying Jin#, Yao Tang#, Shao-Hua Fan, Zi-Feng Zhang, Fang Wang, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. microRNA-136 inhibits proliferation and promotes apoptosis and radiosensitivity of cervical carcinoma through the NF-κB pathway by targeting E2F1. Life Sciences, 2018, 199:167-178.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文20:“Yong-Jian Wang#, Min Shen#, Shan Wang#, Xin Wen, Xin-Rui Han, Zi-Feng Zhang, Hui Li, Fei Wang, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Inhibition of the TGF-β1/Smad signaling pathway protects against cartilage injury and osteoarthritis in a rat model. Life Sciences, 2017, 189:106-113.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文21:“Xiao-Fei Jin#, Shan Wang#, Min Shen#, Xin Wen, Xin-Rui Han, Jun-Chang Wu, Gao-Zhuo Tang, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Effects of rehabilitation training on apoptosis of nerve cells and the recovery of neural and motor functions in rats with ischemic stroke through the PI3K/Akt and Nrf2/ARE signaling pathways. Brain Research Bulletin, 2017, 134:236-245.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文22:“Pei-Ying Jin#, Hong-Jie Lu#, Yao Tang#, Shao-Hua Fan, Zi-Feng Zhang, Yan Wang, Xu-Ning Li, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. The effect of DNA-PKcs gene silencing on proliferation, migration, invasion and apoptosis, and in vivo tumorigenicity of human osteosarcoma MG-63 cells. Biomedicine & Pharmacotherapy, 2017, 96:1324-1334.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文23:“Qi-Hang Cai#, Yao Tang#, Shao-Hua Fan, Zi-Feng Zhang, Hong Li, Shao-Qiang Huang, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. In vivo effects of dexmedetomidine on immune function and tumor growth in rats with ovarian cancer through inhibiting the p38MAPK/NF-κB signaling pathway. Biomedicine & Pharmacotherapy, 2017, 95:1830-1837.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文24:“Min Shen#, Shan Wang#, Xin Wen, Xin-Rui Han, Yong-Jian Wang, Xiu-Min Zhou, Man-He Zhang, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Dexmedetomidine exerts neuroprotective effect via the activation of the PI3K/Akt/mTOR signaling pathway in rats with traumatic brain injury. Biomedicine & Pharmacotherapy, 2017, 95(3):885-893.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文25:“Dong-Mei Wu#, Shan Wang#, Xin Wen, Xin-Rui Han, Yong-Jian Wang, Shao-Hua Fan, Zi-Feng Zhang, Qun Shan, Jun Lu*, Yuan-Lin Zheng*. Long noncoding RNA nuclear enriched abundant transcript 1 impacts cell proliferation, invasion, and migration of glioma through regulating miR-139-5p/CDK6. Journal of Cellular Biochemistry, 2019, 234(5):5972-5987.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文26:“Dong-Mei Wu#, Xin Wen#, Yong-Jian Wang, Xin-Rui Han, Shan Wang, Min Shen, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Jun Lu*, Gui-Quan Chen*, Yuan-Lin Zheng*. Effect of microRNA-186 on oxidative stress injury of neuron by targeting interleukin 2 through the janus kinase-signal transducer and activator of transcription pathway in a rat model of Alzheimer’s disease. Journal of Cellular Biochemistry, 2018, 233(12):9488-9502.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文27:“Shan Wang#, Xin Wen#, Xin-Rui Han#, Yong-Jian Wang, Min Shen, Shao-Hua Fan, Juan Zhuang, Wei Xu, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. MicroRNA-30d preserves pancreatic islet β-cell function through negative regulation of the JNK signaling pathway via SOCS3 in mice with streptozotocin-induced diabetes mellitus. Journal of Cellular Biochemistry, 2018, 233(9):7343-7355.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文28:“Xin Wen#, Xin-Rui Han#, Yong-Jian Wang#, Shan Wang, Min Shen, Zi-Feng Zhang, Shao-Hua Fan, Qun Shan, Liang Wang, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. MicroRNA-421 suppresses the apoptosis and autophagy of hippocampal neurons in epilepsy mice model by inhibition of the TLR/MYD88 pathway. Journal of Cellular Biochemistry, 2018, 233(9):7022-7034.”(标注基金号81271225、81171012、81571055、81400902、81570531)

  论文29:“Xin-Rui Han#, Xin Wen#, Yong-Jian Wang#, Shan Wang, Min Shen, Zi-Feng Zhang, Shao-Hua Fan, Qun Shan, Liang Wang, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Protective effects of microRNA-431 against cerebral ischemia-reperfusion injury in rats by targeting the Rho/Rho-kinase signaling pathway. Journal of Cellular Biochemistry, 2018, 233(8):5895-5907.”(标注基金号81271225、81171012、30950031、81571055、81400902、81570531、81672731)

  论文30:“Dong-Mei Wu#, Yong-Jian Wang#, Xin-Rui Han, Xin Wen, Shan Wang, Min Shen, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Jun Lu*, Yuan-Lin Zheng*. LncRNA LINC00880 promotes cell proliferation, migration, and invasion while inhibiting apoptosis by targeting CACNG5 through the MAPK signaling pathway in spinal cord ependymoma. Journal of Cellular Biochemistry, 2018, 233(9):6689-6704.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文31:“Xin Wen#, Xin-Rui Han#, Yong-Jian Wang#, Shan Wang, Min Shen, Zi-Feng Zhang, Shao-Hua Fan, Qun Shan, Liang Wang, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Dong-Mei Wu*, Jun Lu*, and Yuan-Lin Zheng*. Down-regulated long non-coding RNA ANRIL restores the learning and memory abilities and rescues hippocampal pyramidal neurons from apoptosis in streptozotocin-induced diabetic rats via the NF-κB signaling. Journal of Cellular Biochemistry, 2018, 119(7):5821-5833.”(标注基金号81271225、81171012、30950031、81571055、81400902、81570531、81672731)

  论文32:“Xin Wen#, Xin-Rui Han#, Yong-Jian Wang#, Shao-Hua Fan, Zi-Feng Zhang, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Effects of S100A12 gene silencing on serum levels of anti-inflammatory/pro-inflammatory cytokines in septic rats through the ERK signaling pathway. Journal of Cellular Biochemistry, 2018, 119(5):4038-4049.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文33:“Gui-Hong Zheng#, Xin Wen#, Yong-Jian Wang#, Xin-Rui Han#, Qun Shan, Wang Li, Tian Zhao, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. MicroRNA-381-induced down regulation of CXCR4 promotes the proliferation of renal tubular epithelial cells in rat models of renal ischemia reperfusion injury. Journal of Cellular Biochemistry, 2018, 119(4):3149-3161.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文34:“Xin Wen#, Xin-Rui Han#, Yong-Jian Wang#, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Qiao Wu, Jun-Hua Tan, Dong-Mei Wu*, Jun Lu*, Yuan-Lin Zheng*. Effects of long noncoding RNA SPRY4-IT1-mediated EZH2 on the invasion and migration of lung adenocarcinoma. Journal of Cellular Biochemistry, 2018, 119(2):1827-1840.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  论文35:“Dong-Mei Wu, Xiao-Wu Hong, Xin Wen, Xin-Rui Han, Shan Wang, Yong-Jian Wang, Min Shen, Shao-Hua Fan, Juan Zhuang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Chun-Hui Sun, Jun Lu*, Yuan-Lin Zheng*. MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. IUBMB Life, 2019, 71(1):81-92.”(标注基金号81271225、31201039、81171012、30950031、81571055、81400902)

  经依托单位调查,上述35篇涉事论文均存在图片不当使用或数据造假的问题,存在问题的图片或数据均由第三方公司提供。35篇涉事论文中,有34篇(除论文21外)还存在未经同意使用他人署名的问题,论文4、5、9、12、30、34还存在编造研究过程的问题。吴冬梅作为上述35篇涉事论文的撰写人,其中12篇论文(论文2、8、9、10、11、12、14、15、25、26、30、35)的第一作者和22篇论文(论文1、4、5、6、7、13、16、17、18、19、20、21、22、23、24、27、28、29、31、32、33、34)的通讯作者,应对图片或数据造假的客观结果、未经同意使用他人署名和编造研究过程负主要责任;郑元林和陆军作为35篇涉事论文的共同通讯作者,疏于审核,负次要责任。此外,吴冬梅将4篇涉事论文(论文21、24、28、29)列入其国家自然科学基金项目(批准号81400902)结题报告中,郑元林将9篇涉事论文(论文6、8、10、13、21、24、26、28、29)列入其国家自然科学基金项目(批准号81571055)结题报告中,均应对在结题报告中存在虚假信息的客观结果负责。

  经国家自然科学基金委员会监督委员会五届十二次会议(生命医学专业委员会)审议、国家自然科学基金委员会2022年第2次委务会议审定,决定依照《国家自然科学基金条例》第三十五条第四项、《国家自然科学基金委员会监督委员会对科学基金工作中不端行为的处理办法(试行)》第十七条第三、四项、第九条,撤销吴冬梅国家自然科学基金项目“TRPV4介导软骨藻酸处理致小鼠认知缺陷的分子机制”(批准号81400902),追回已拨资金,永久取消吴冬梅国家自然科学基金项目申请资格(自2022年1月18日起),给予吴冬梅通报批评;决定依照《国家自然科学基金条例》第三十五条第四项,并参照《国家自然科学基金委员会监督委员会对科学基金工作中不端行为的处理办法(试行)》第十七条第三、四项,撤销郑元林国家自然科学基金项目“HDAC6激活HMGB1/RAGE信号轴介导Ⅱ型糖尿病小鼠认知缺陷的机制研究”(批准号81571055),追回已拨资金,取消郑元林国家自然科学基金项目申请资格5年(2022年1月18日至2027年1月17日),给予郑元林通报批评;决定参照《国家自然科学基金委员会监督委员会对科学基金工作中不端行为的处理办法(试行)》第十七条第三、四项,取消陆军国家自然科学基金项目申请资格5年(2022年1月18日至2027年1月17日),给予陆军通报批评。

  国家自然科学基金委员会

  2022年3月30日


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